Reference

All Peptides — 15 compounds reviewed

Each entry includes mechanism, evidence summary, FDA / regulatory status, safety profile and 2026 update. Organized by therapeutic category.

Anti-Aging & Longevity

Not FDA-approved · Used in Rus

Epitalon

Tetrapeptide developed for telomerase activation and longevity

Not a peptide · cofactor · Ava

NAD+

Coenzyme central to mitochondrial energy and DNA repair

Anti-Aging & Skin

OTC cosmetic ingredient · Not

GHK-Cu

Copper-binding tripeptide · best-evidenced cosmetic peptide

Cognitive & Mood

Not FDA-approved · Approved in

Selank

Russian-developed nootropic peptide for anxiety and cognition

Not FDA-approved · Approved in

Semax

Russian neuroprotective peptide · ACTH 4-10 derivative

Growth Hormone

Not FDA-approved · Investigati

Ipamorelin

Selective ghrelin receptor agonist · stimulates GH without prolactin/cortisol increase

Not FDA-approved · Investigati

CJC-1295

Long-acting GHRH analog · pairs with ipamorelin for sustained GH release

Not FDA-approved · Investigati

GHRP-6

Original ghrelin mimetic · stimulates GH and appetite

Healing & Repair

Not FDA-approved · Category 2

BPC-157

The 15-amino-acid healing peptide derived from gastric juice protein

Not FDA-approved · Off-WADA li

TB-500

Synthetic fragment of Thymosin Beta-4 used in tissue repair research

Immune Modulation

Not FDA-approved · Approved in

Thymosin Alpha-1

28-amino-acid immunomodulator · approved in 35+ countries (not US)

Metabolic & Weight

FDA-approved · Ozempic (T2D) 2

Semaglutide

The most-studied GLP-1 agonist · FDA-approved for type 2 diabetes and obesity

FDA-approved · Mounjaro (T2D)

Tirzepatide

Dual GLP-1 + GIP receptor agonist · most effective weight-loss peptide approved

Not FDA-approved · Investigati

MOTS-c

16-amino-acid mitochondrial peptide · metabolic regulator

Other

Not FDA-approved · Banned in E

Melanotan II

Synthetic α-MSH analog · originally developed for melanoma prevention